Complexins Living Up to Their Name— New Light on Their Role in Exocytosis
نویسندگان
چکیده
Ca(2+)-dependent exocytosis of synaptic vesicles is mediated by the SNARE proteins synaptobrevin/VAMP, SNAP-25, and syntaxin. SNARE function is controlled by conserved regulatory proteins, including the complexins. In a study by Xue et al. in this issue of Neuron, contradictory data from Drosophila and mouse complexin mutants have been resolved, revealing a complex pattern of facilitatory and inhibitory domains.
منابع مشابه
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ورودعنوان ژورنال:
- Neuron
دوره 64 شماره
صفحات -
تاریخ انتشار 2009